Overall responsibility for the technical conduct of the study, as well as for the documentation: 

 1. Act as main point of contact for in vivo studies service CRO；

 2. Lead and coordinate study designs and timelines/resources for in vivo efficacy operations；

 3. Develop models to test the activity of iPSC-CAR-NK cell in combination with established therapeutic agents and perform in-depth characterization of mechanism in these models；

 4. Compliance with IACUC and regulatory guidance；

 5. Contribute to the preparation of IND applications and other regulatory documents, as appropriate；

 6. Must think critically and creatively, determine appropriate resources for resolution of problems and have strong organizational and planning skills；

 7. Management of animal model portfolio；

 8. Design, develop, and implement high quality and reproducible animal models to address key mechanistic and pharmacological scientific questions；

 9. Understanding the pathology and clinical relevance of disease models；

 10. Provide scientific input into the preclinical animal models and their in vivo applications supporting the programs；

 11. Management of disease model database；

 12. Generate IACUC protocols when required for new procedures；

 13. Continuously and proactively evaluate and implement state-of-the-art technologies, approaches;

 14. Independently performs literature searches and keeps abreast of literature in own field Establish systematic and efficient process and develop SOP. 

 Position Qualifications

 1. Ph.D. in tumor biology, pharmacology, immunology, or related fields with minimum 6 years of research experience in a pharma industry setting

 2. Prior hands-on experience in in-life portion of rodent studies (drug administration, tissue dissection, etc.) is preferred

 3. Strong expertise in designing and executing in vivo pharmacology experiments Thorough knowledge of relevant, current in vivo methods and assays used in drug discovery research.

 4.Familer with animal physiology, histology, and pathology 

 5. Broad understanding of FDA, ICH guidelines, and experience with IND submission

 6. Has flexibility to accommodate to fast-paced work environment and deadlines; and ability to work under specific time constraints.

 7. Excellent analytical and organizational skills.

 8. Excellent communications skills – bilingual in English and Chinese.